Organic Acids
Medchemexpress LLC Myr-FEEERA-OH (TFA) | 990.15 | 25 MG
mP6 (Myr-FEEERA-OH) is a myristoylated peptide. It inhibits the interaction of Gα13 with integrin β3 without disrupting talin-dependent integrin function, and can block the GTP usage of Rac1, Rap1, and Rab7.
- Effectively inhibits the infection of CHO-A24 cells
- Myristoylated peptide
- Inhibits interaction of Gα13 with integrin β3
- Blocks GTP usage of Rac1, Rap1, and Rab7
Medchemexpress LLC Gln-AMS TFA | 99.85% | 588.47 | 50 MG
Gln-AMS (TFA) is a type Ia aminoacyl-tRNA synthetase (AARS) inhibitor. It specifically inhibits glutaminyl-tRNA synthetase (GlnRS) with a Ki of 1.32 μM. This product is intended for research use only.
- Inhibits glutaminyl-tRNA synthetase.
- High purity of 99.85%.
- Available in various quantities.
- Data sheet, COA, SDS, and handling instructions provided.
- Supported by customer reviews and publications.
Medchemexpress LLC Α-MSH (TFA) | 171869-93-5 | 98.5% | 25 MG
α-MSH TFA (α-Melanocyte-Stimulating Hormone TFA) is an endogenous neuropeptide that acts as a melanocortin receptor 4 (MC4R) agonist. It exhibits anti-inflammatory and antipyretic activities, being a post-translational derivative of pro-opiomelanocortin (POMC).
- Modulates CNS inflammation by acting directly on melanocortin receptors in glial cells.
- Modulates NFκB activation.
- Inhibits translocation of transcription factor κB to the nucleus.
- Effectively modulates inflammatory reactions when given systemically.
Sigma Aldrich Fine Chemicals Biosciences Trifluoroacetic acid 99 fo100G
TRIFLUOROACETIC Trifluoroacetic acid 99 fo100G
Medchemexpress LLC Gmprga Tfa | 98.1% | 5 MG
GMPRGA TFA is the trifluoroacetic acid (TFA) salt form of GMPRGA. It is known to recognize spAimR in the bacterial cytosol, a process that induces lysogeny.
- TFA salt form
- Recognizes spAimR in bacterial cytosol
- Induces lysogeny
- Functions as an inhibitor
- Part of bacterial lysis-lysogeny studies
- Classified as an antimicrobial peptide
Medchemexpress LLC Dendrotoxin K TFA | 99.5% | 6559.66 | 5 MG
Dendrotoxin K TFA is a Kv1.1 channel blocker. It determines glutamate release in CA3 neurons in a time-dependent manner through the control of the presynaptic spike waveform. The product is a solid, white to off-white in color.
- Kv1.1 channel blocker
- Determines glutamate release in CA3 neurons
- Solid appearance
- White to off-white color
Medchemexpress LLC VU0364572 (TFA) | 1240514-89-9 | 99.3% | 487.51 | 25 MG
VU0364572 TFA is an orally active and selective allosteric agonist of the M1 muscarinic receptor with an EC50 of 0.11 μM. It demonstrates neuroprotective potential for preventing memory impairments and reducing neuropathology in Alzheimer's Disease and is CNS penetrant.
- Orally active and selective allosteric agonist of the M1 muscarinic receptor.
- Neuroprotective potential for preventing memory impairments.
- Reduces neuropathology in Alzheimer's Disease.
- CNS penetrant.
Medchemexpress LLC TFLLR-NH2(TFA) | 1313730-19-6 | 99.6% | 761.83 | 10 MG
TFLLR-NH2(TFA) is a selective PAR1 agonist with an EC50 of 1.9 μM, intended for research use. It stimulates concentration-dependent increases in intracellular calcium and promotes upregulation of E-cadherin expression in SW620 cells. In vivo, it can induce oedema and extravasation in various organs.
- Selective PAR1 agonist (EC50 of 1.9 μM)
- Induces concentration-dependent increases in intracellular calcium
- Upregulates E-cadherin expression in SW620 cells
- Stimulates secreted TGF-β1 in platelet cultures
- Can induce oedema and extravasation in animal models
- Stable for 2 years as powder at -80°C
- Stable for 6 months in solvent at -80°C
Medchemexpress LLC MI-1061 TFA | 1410737-35-7 | 97.5% | 696.47 | C32H27Cl2F4N3O6 | 10MM 1ML
MI-1061 TFA is the trifluoroacetate salt of MI-1061, a potent, orally bioavailable inhibitor of the MDM2-p53 interaction (reported IC50 = 4.4 nM; Ki = 0.16 nM). The compound is offered as a solid and as a ready-to-use 10 mM solution in DMSO (1 mL) for in vitro assays, and the manufacturer provides solubility and in vivo formulation guidance. Typical uses include biochemical and cell-based studies of p53 pathway modulation.
- Potent MDM2-p53 interaction inhibitor (IC50 4.4 nM).
- Available as solid and as a 10 mM solution in DMSO for immediate use.
- High purity (approximately 97.5%), suitable for research assays.
- Soluble in DMSO (reported solubility 120 mg/mL), enabling concentrated stocks.
- Manufacturer provides recommended stock concentrations and in vivo vehicle guidance.
Medchemexpress LLC TP-5801 (TFA) | 99.6% | 641.48 | 50 MG
TP-5801 TFA is an orally active TNK1 (non-receptor tyrosine kinase) inhibitor with an IC50 of 1.40 nM. It demonstrates significant anti-tumor activity both in vitro and in vivo. This compound is stable under recommended storage conditions and is for research use only.
- Inhibits TNK1-driven, BCR-ABL-driven, and IL-3-driven Ba/F3 cell growth
- Inhibits TNK1-dependent L540 cell growth at low nanomolar levels
- Shows efficacy in mouse survival models with no observed toxicity
- Reduces localized tumor growth and phospho-STAT3 in xenograft models
Medchemexpress LLC RI(dl)-2 TFA | 98.0% | 1 ML
RI(dl)-2 TFA is a potent and selective RAD51-mediated D-loop formation inhibitor with an IC50 of 11.1 μM. It inhibits homologous recombination (HR) activity in human cells with an IC50 of 3.0 μM and does not influence RAD51 binding to ssDNA.
- Potent and selective RAD51-mediated D-loop formation inhibitor
- IC50 of 11.1 μM for D-loop formation
- Inhibits homologous recombination (HR) activity in human cells
- Does not influence RAD51 binding to ssDNA
- Stabilizes nucleoprotein filaments in a nonfunctional state
- Shielded from pathways promoting single-strand annealing
Aobchem 4-(2-Fluoroethyl)benzoic acid | ≥95% | CAS 819883-84-6 | C9H9FO2 | 500mg
4-(2-Fluoroethyl)benzoic acid | ≥95% | CAS 819883-84-6 | C9H9FO2 | 500mg
Aobchem 3-(3-Fluorophenoxy)benzoic acid | 95% | CAS 1184171-43-4 | C13H9FO3 | 5g
3-(3-Fluorophenoxy)benzoic acid | 95% | CAS 1184171-43-4 | C13H9FO3 | 5g
Aobchem Benzoic acid 4-(4-hydroxy-1-butyn-1-yl)- methyl ester | ≥95% | CAS 123910-86-1 | C12H12O3 | 500mg
Benzoic acid 4-(4-hydroxy-1-butyn-1-yl)- methyl ester | ≥95% | CAS 123910-86-1 | C12H12O3 | 500mg
Aobchem Benzoic acid 4-(4-hydroxy-1-butyn-1-yl)- methyl ester | ≥95% | CAS 123910-86-1 | C12H12O3 | 250mg
Benzoic acid 4-(4-hydroxy-1-butyn-1-yl)- methyl ester | ≥95% | CAS 123910-86-1 | C12H12O3 | 250mg